CELL INTELLIGENCE · 肿瘤细胞治疗研究

细菌 RNA 下调肿瘤细胞系 MHC-I 并促进 NK 反应、延缓肿瘤生长

Bacterial RNA downregulates MHC-I in tumor cell lines, promoting NK response and delaying tumor growth.

超分子免疫调节水凝胶剂以持久内源性免疫增强 CAR-T 疗法实现实体瘤清除

Supramolecular immunomodulatory hydrogelator potentiates CAR-T therapy with long-lasting endogenous immunity toward solid tumor eradication.

αvβ3 CAR-T 细胞同时靶向肿瘤和转移灶，在黑色素瘤和三阴性乳腺癌的临床前模型中产生高度有效的控制

αvβ3 CAR-T Cells Simultaneously Targeting Tumor and Metastases Produce Highly Effective Control in Preclinical Models of Melanoma and Triple-Negative

ROBO1 CAR-NK92 细胞中 Cbl-b 敲除增强其抗肿瘤疗效

Ablation of Cbl-b in ROBO1 CAR-NK92 Cells Enhances Their Antitumor Efficacy.

达沙替尼促进γδ T 细胞扩增和记忆表型，并增强抗肿瘤免疫

Dasatinib boosts γδ T cell expansion and memory phenotypes with enhanced antitumor immunity.

淋巴毒素 β 受体在实体瘤免疫及治疗靶向中的多效性与多细胞作用

Pleiotropic and multicellular roles of lymphotoxin beta receptor in solid tumor immunity and therapeutic targeting.

基于 CAR-T/NK/M 的肿瘤联合治疗：全面综述

CAR-T/NK/M-based combination therapies in cancer: A comprehensive review.

通过新型嵌合抗原受体 (CAR)-T 细胞平台靶向 TGF-β 对接受体糖蛋白 A 重复序列主要蛋白 (GARP) 治疗胶质母细胞瘤

Targeting TGFβ docking receptor glycoprotein A repetitions predominant (GARP) via novel chimeric antigen receptor (CAR)-T cell platform to treat gliob

GARP-LTGF 在 GBM 的发生和预后中发挥关键作用，靶向 GARP 的 CAR-T 治疗在小鼠原位 GBM 模型中显示出有前景的疗效和安全性。

靶向 HER2 阳性实体瘤的纳米抗体 CAR-T 细胞临床前开发与筛选

Preclinical development and selection of nanobody-based CAR-T cells targeting HER2-positive solid tumors.

NK 细胞疫苗在实体瘤临床试验中的优势：多种生物学策略与技术的实施

The advantages of NK cell vaccines in solid carcinoma clinical trials: conducted by various biology strategy and technology.