CELL INTELLIGENCE · 肿瘤细胞治疗研究

靶向 O-糖基化纤连蛋白的 CAR T 细胞表现出强效溶细胞活性，并与肿瘤 Toll 样受体激动作用联合克服肿瘤耐药

CAR T Cells Targeting O-Glycosylated Fibronectin Exhibit Potent Cytolytic Activity and Combine with Tumoral Toll-Like Receptor Agonism to Overcome Tum

肿瘤重塑细胞外基质（ECM）与糖基化，产生在正常成人组织中可检测性受限或有限的表位。