成人侵袭性 T 大颗粒淋巴细胞白血病伴异常自然杀伤 T 细胞表型及新型细胞系的建立
Aggressive T-large granular lymphocytic leukemia with an aberrant natural killer T-cell phenotype in an adult and derivation of a novel cell line.
肿瘤细胞治疗研究
FRONTIER PAPERS
近 5 年肿瘤细胞治疗领域的研究论文。默认按评分排序(权威性 + 新鲜度)。
Aggressive T-large granular lymphocytic leukemia with an aberrant natural killer T-cell phenotype in an adult and derivation of a novel cell line.
Invariant Natural Killer T Cell Therapy Attenuates Systemic Inflammation and Improves Transarterial Chemoembolization Outcomes in Hepatocellular Carci
Mitochondrial metabolism-associated biomarkers in oral lichen planus and oral squamous cell carcinoma.
The increased co-expression of SLC7A11 and PD-L1 was associated with poor prognosis in extranodal natural killer T-cell lymphoma patients.
Identification of GADD45B, HMGB3, LMNB2, and MFAP5 as lactylation-related prognostic markers for survival prediction in esophageal cancer.
我们确定了四个与乳酸化活性评分相关的基因,它们可作为 ESCA 的独立预后候选基因。这些 LRGs 有望成为 ESCA 的潜在治疗靶点和预后生物标志物。
Innate immune dysregulation in multiple myeloma: molecular basis and mechanistic interventions.
先天免疫应被视为 MM 发病机制和治疗的核心组成部分,而非次要因素。对先天免疫失调机制的深入理解,不仅可能完善当前的免疫治疗策略,还可能启发新的治疗范式,最终改善 MM 的长期疾病控制。
Integrated transcriptomics, network pharmacology and clinical expression validation reveal the prognostic significance of PANoptosis-related genes in
我们的结果表明,包括 SLC2A1、SMS、CCNA2、CDC25C、RNASE1、NR3C2、CAT 和 ADA 在内的 8 个生物标志物与 LUAD 中的 PANoptosis 相关。
Efficacy and Safety of Immune Checkpoint Inhibitors in the Treatment of Hematologic Malignancies: An Umbrella Review of Systematic Reviews and Meta-An
ICIs 在几种血液系统恶性肿瘤中显示出有前景的治疗潜力,尤其是 R/R NKT、MM、R/R CLL 和 R/R PMBCL。虽然安全性特征总体良好,但某些方案与可管理的毒性相关。未来研究应侧重于优化联合治疗、完善患者选择标准,并解决研究异质性,以增强 ICIs 在血液系统癌症中的临床应用。
Oncogenic and immunological roles of LAMP5 across cancers and its potential utility in bladder cancer.
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