αvβ3 CAR-T 细胞同时靶向肿瘤和转移灶,在黑色素瘤和三阴性乳腺癌的临床前模型中产生高度有效的控制
αvβ3 CAR-T Cells Simultaneously Targeting Tumor and Metastases Produce Highly Effective Control in Preclinical Models of Melanoma and Triple-Negative
FRONTIER PAPERS
αvβ3 CAR-T Cells Simultaneously Targeting Tumor and Metastases Produce Highly Effective Control in Preclinical Models of Melanoma and Triple-Negative
TGF-β signalling limits effector function capacity of NK cell anti-tumour immunity in human bladder cancer.
本研究强调富含 TGF-β的膀胱癌通过下调 CD16 抑制 NK 细胞介导的 ADCC。抑制 TGF-β为逆转免疫抑制和增强膀胱癌中 NK 细胞的杀肿瘤能力提供了新途径。
Cytotoxic granzyme C-expressing ILC1s contribute to antitumor immunity and neonatal autoimmunity.
In vitro characterization of a novel anti-GD2/ROR1 bispecific antibody exhibiting tumor cell killing efficacy in neuroblastoma cross-cancer activity i
G/R-001 BsAb 可同时结合 GD2 和 ROR1,并在体外显示出显著的抗肿瘤活性。这些结果为 G/R-001 作为新型抗肿瘤治疗药物的进一步开发提供了有力的实验证据。
Current immunotherapeutic approaches to diffuse intrinsic pontine glioma.
Clinical significance of regulatory T cells and T lymphocyte subsets in peripheral blood in neoadjuvant chemotherapy for breast cancer.
Amplification of ERBB2 (HER2) in embryonal rhabdomyosarcoma: A potential treatment target in rare cases?
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