CELL INTELLIGENCE · 肿瘤细胞治疗研究

一种用于克服非小细胞肺癌治疗中抗原异质性的多靶向 CAR-T 细胞平台

A Multi-Targeting Chimeric Antigen Receptor-T Cell Platform to Overcome Antigen Heterogeneity in the Treatment of Non-Small Cell Lung Cancer.

靶向糖抗原 CD176 的可诱导分泌 IL-12 或 IL-18 的 CAR-T 细胞在临床前模型中显示出对非小细胞肺癌的强效活性

Inducible IL-12 or IL-18 secreting CAR T cells targeting the glyco-antigen CD176 exhibit potent activity against non-small cell lung cancer in preclin

靶向 KRAS 突变肺癌

Targeting KRAS-Mutant Lung Cancers.

CD200-CD200R 作为实体瘤中的髓系免疫检查点：机制、情境依赖性功能及治疗机会

CD200-CD200R as a myeloid immune checkpoint in solid tumors: mechanisms, context-dependent functions, and therapeutic opportunities.

当前对周围血免疫细胞表型在癌症治疗耐药中作用的认识

Current Insights into the Role of Peripheral Blood Immune Cell Phenotypes in Resistance to Cancer Therapies.

肿瘤细胞表达的 OX40L 增强非小细胞肺癌中 PD-1 轴阻断的疗效

Tumor cell-expressed OX40L enhances the efficacy of PD-1 axis blockade in non-small cell lung cancer.

肿瘤细胞表达的 OX40L 有助于增强 NSCLC 患者对 PD-1 阻断治疗的疗效。这些发现可能开辟新的治疗途径，并可能有助于改善该疾病的免疫治疗个体化。

癌症中的 B 细胞：功能、机制与治疗进展

B cells in cancer: functions, mechanisms and therapeutic advances.

既往有口腔扁平苔藓的患者从 PD-1 转换为 PD-L1 后泛发性皮肤扁平苔藓复发：一例病例报告

Recurrence of generalized cutaneous lichen planus after switching from PD-1 to PD-L1 in a patient with pre-existing oral lichen planus: a case report.

T 细胞重定向疗法在肺癌中的应用——临床试验的综合分析

T-cell redirecting therapies in lung cancer - a comprehensive analysis of clinical trials.

基于 mRNA 的实体瘤癌症疫苗的临床转化

Clinical translation of mRNA-based cancer vaccines for solid tumors.