基于 PBPK-PD 模型表征有或无既往淋巴细胞清除化疗的实体瘤患者中 CAR-T 细胞动力学与疗效
Characterization of CAR-T cellular kinetics and efficacy in solid tumor patients with and without prior lymphodepletion chemotherapy using a PBPK-PD m
肿瘤细胞治疗研究
FRONTIER PAPERS
近 5 年肿瘤细胞治疗领域的研究论文。默认按评分排序(权威性 + 新鲜度)。
Characterization of CAR-T cellular kinetics and efficacy in solid tumor patients with and without prior lymphodepletion chemotherapy using a PBPK-PD m
Integrative multi-omics analysis reveals a novel subtype of hepatocellular carcinoma with biological and clinical relevance.
本研究构建了一个稳健的 HCC 预后模型,并在单细胞水平上识别出新的亚组,可能有助于评估 HCC 患者的预后风险并促进个性化药物治疗。
rhIL-7-hyFc, a long-acting interleukin-7, improves efficacy of CAR-T cell therapy in solid tumors.
本研究为 NT-I7 联合 CAR-T 细胞治疗人类实体瘤提供了依据。
Mesothelin CAR T Cells Secreting Anti-FAP/Anti-CD3 Molecules Efficiently Target Pancreatic Adenocarcinoma and its Stroma.
CAR-TEAM 细胞能够实现对肿瘤基质的修饰,从而导致 PDAC 肿瘤的清除增加。这种方法为胰腺癌提供了一种有前景的治疗选择。
Advances in CAR T Cell Therapy for Non-Small Cell Lung Cancer.
Immunotherapy for hepatobiliary cancers: Emerging targets and translational advances.
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