滤泡性淋巴瘤患者接受 CAR-T 细胞治疗后双特异性抗体治疗的真实世界结局
Real-world outcomes of bispecific antibody therapy after chimeric antigen receptor T-cell therapy in follicular lymphoma.
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FOR TREATMENT
按「中国试验优先 → 正在招募 → 更新更近」排序。信息来自 ClinicalTrials.gov 与 CDE 公开登记。能否入组、费用与可及性,以登记原文和主治医生判断为准。
FOR RESEARCH
Real-world outcomes of bispecific antibody therapy after chimeric antigen receptor T-cell therapy in follicular lymphoma.
Follicular Lymphoma: Novel Therapies and Strategies for Optimal Therapeutic Sequencing.
双特异性抗体(mosunetuzumab、epcoritamab)在重度经治FL中已显示出持久的完全缓解,且毒性特征可控。
Systematic review and meta-analysis: CAR-T vs bispecific antibody as third or later-line therapy for follicular lymphoma.
在筛选的 3960 条记录中,12 项研究符合纳入标准——其中 7 项涉及 CAR-T,5 项涉及 BsAbs。
Treatment of relapsed and refractory follicular lymphoma: which treatment for which patient for which line of therapy?
近期进展已改变复发和难治性滤泡性淋巴瘤的治疗格局。
The future of follicular lymphoma management: strategies on the horizon.
滤泡性淋巴瘤(FL)是最常见的惰性淋巴瘤亚型,近年来其治疗取得了进展,中位总生存期显著改善。
Treatment and survival outcomes for patients with follicular lymphoma and POD24: a systematic review and meta-analysis.
24 个月内疾病进展(POD24)的滤泡性淋巴瘤预后不良,是临床上的挑战。
Matching-adjusted indirect comparison of efficacy and safety of lisocabtagene maraleucel and mosunetuzumab for the treatment of third-line or later re
研究结果凸显了liso-cel相较于mosunetuzumab作为R/R FL三线及以上治疗方案的潜在正向获益-风险特征。
Building the future management of follicular lymphoma with T-cell-redirecting strategies.
滤泡性淋巴瘤(FL)通常需要多线治疗,而传统化学免疫治疗的疾病控制效果仍远不理想。
Alternative splicing of its 5'-UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies.
CD19和CD22中编码外显子的异常跳跃损害了B细胞恶性肿瘤对免疫治疗的反应。
NCCN Guidelines® Insights: B-Cell Lymphomas, Version 6.2023.
新型靶向治疗(小分子抑制剂、抗体偶联药物和 CD19 靶向治疗)已改变复发/难治性 B 细胞淋巴瘤的治疗格局。
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