肿瘤细胞治疗研究
英文原题：T-Cell-Replete Haploidentical Hematopoietic Stem Cell Transplantation for Relapsed B-Cell Precursor Acute Lymphoblastic Leukemia After CAR-T Therapy.
T-Cell-Replete Haploidentical Hematopoietic Stem Cell Transplantation for Relapsed B-Cell Precursor Acute Lymphoblastic Leukemia After CAR-T Therapy.
分数与星级只用于站内排序 —— 不代表疗效、安全性或个人适用性。
CAR-T 细胞治疗后复发的急性淋巴细胞白血病（ALL）是一项重大治疗挑战，尤其是在儿童人群中。
CAR-T 细胞治疗后复发的急性淋巴细胞白血病（ALL）构成重大治疗挑战，儿童患者尤为如此。本报告介绍3例CAR-T 治疗后复发的B细胞前体ALL病例，均成功接受含T细胞的单倍型相合造血干细胞移植（TCR-haplo-HSCT）。该方法在长期生存方面显示良好结局，提示TCR-haplo-HSCT有望作为CAR-T 治疗后儿童复发ALL的巩固治疗。
Recurrent acute lymphoblastic leukemia (ALL) following chimeric antigen receptor T-cell (CAR-T) therapy represents a significant therapeutic challenge, particularly in pediatric populations. This report describes three cases of B-cell precursor ALL that recurred after CAR-T therapy and were successfully treated with T-cell-replete haploidentical hematopoietic stem cell transplantation (TCR-haplo-HSCT). This approach has shown promising outcomes in terms of long-term survival, highlighting the potential of TCR-haplo-HSCT as consolidation therapy for recurrent pediatric ALL post-CAR-T therapy.
MEMBER ACCOUNT
登录成功会直接打开下一页。
