肿瘤细胞治疗研究
英文原题：Advances in NK cell therapy for multiple myeloma.
Advances in NK cell therapy for multiple myeloma.
分数与星级只用于站内排序 —— 不代表疗效、安全性或个人适用性。
多发性骨髓瘤（MM）是一种恶性疾病，其特征为克隆性浆细胞异常增殖。MM患者的NK细胞数量和功能受到抑制，导致免疫监视及骨髓瘤细胞清除能力降低。恢复或增强NK细胞对骨髓瘤细胞的杀伤作用，是MM免疫治疗的重要策略。目前，NK细胞过继疗法和CAR-NK疗法的临床前及临床研究均已取得一系列重大进展。本文介绍MM的各种治疗策略现状及NK细胞在MM中的作用，并综述NK细胞免疫疗法治疗MM的最新结果。
Multiple myeloma (MM) is a malignant disease in which clonal plasma cells proliferate abnormally. In patients with MM, the number and function of NK cells are suppressed, resulting in reduced immune surveillance and clearance of myeloma cells. Restoring or enhancing the killing effect of NK cells on myeloma cells is an important strategy for MM immunotherapy.
At present, a series of great progress has been made in preclinical and clinical studies for NK cell adoptive therapy and CAR-NK therapy. This article introduces the current status of various treatment strategies for MM, NK cells in MM, and reviews the latest results of NK cell immunotherapy for MM.
MEMBER ACCOUNT
登录成功会直接打开下一页。
