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在胶质母细胞瘤中打出 NK 细胞治疗这张牌,IL-21 无可匹敌

英文原题:When playing the NK cell therapy card in glioblastoma, you can't beat interleukin-21.

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When playing the NK cell therapy card in glioblastoma, you can't beat interleukin-21.

PubMed 2024/08/12(内容时间) Cancer Cell Q1 · IF 56.1(JCR 2025)

研究概要

胶质母细胞瘤是最常见的脑癌,5年生存率低于10%。

中文摘要

胶质母细胞瘤是最常见的脑癌,5年生存率低于10%。这一严峻的预后凸显了对新型治疗方法的迫切需求。在本期 Cancer Cell 中,Shanley 等 1 报道了一种创新的工程化策略,以增强 NK 细胞对抗胶质母细胞瘤的免疫力。

展开英文摘要原文

Glioblastoma is the most common brain cancer, with a 5-year survival rate of less than 10%. This grim prognosis highlights the urgent need for novel therapeutic approaches. In this issue of Cancer Cell, Shanley et al. 1 report an innovative engineering strategy to supercharge NK cell immunity against glioblastoma.

论文信息

作者
Huntington ND
单位
Biomedicine Discovery Institute and the Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia; oNKo-Innate Pty. Ltd, Moonee Ponds, VIC 3039, Australia. Electronic address: nicholas.huntington@monash.edu.Australia
期刊
Cancer cell2024 Aug 12
原文标识
PubMed 39137725 · DOI 10.1016/j.ccell.2024.07.003