分泌抗 EpCAM 双特异性 T 细胞衔接器的 CAR T 细胞克服靶向上皮来源癌时的肿瘤异质性
CAR T cells secreting anti-EpCAM bispecific T cell engagers overcome tumor heterogeneity in targeting epithelial-originated carcinomas.
嵌合抗原受体(CAR)T细胞疗法治疗实体瘤的成功有限,部分原因是肿瘤异质性和抗原逃逸。
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CAR T cells secreting anti-EpCAM bispecific T cell engagers overcome tumor heterogeneity in targeting epithelial-originated carcinomas.
嵌合抗原受体(CAR)T细胞疗法治疗实体瘤的成功有限,部分原因是肿瘤异质性和抗原逃逸。
Chimeric Antigen Receptor T cell Therapy and the Immunosuppressive Tumor Microenvironment in Pediatric Sarcoma.
肉瘤是一组多样化的骨和软组织肿瘤,占儿童癌症的10%以上。
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