全人源 EpCAM 特异性 scFv CAR-T 细胞免疫治疗抗胰腺癌的临床前评价
Preclinical evaluation of CAR-T cell immunotherapy with a fully human EpCAM-specific scFv against pancreatic cancer.
胰腺癌是一种侵袭性强、预后差的恶性肿瘤。
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Preclinical evaluation of CAR-T cell immunotherapy with a fully human EpCAM-specific scFv against pancreatic cancer.
胰腺癌是一种侵袭性强、预后差的恶性肿瘤。
Deciphering the secrets of tumor-initiating cells in pancreatic ductal adenocarcinoma microenvironment: mechanisms and therapeutic opportunities.
胰腺导管腺癌 (PDAC) 是一种高度侵袭性的恶性肿瘤,其特征为预后差、对治疗高度耐药以及密集的免疫抑制性肿瘤微环境 (TME)。
The Detection of Immunity against WT1 and SMAD4(P130L) of EpCAM(+) Cancer Cells in Malignant Pleural Effusion.
在MPE中检测到了对EpCAM+胰腺癌细胞中表达的WT1或SMAD4 P130L新抗原产生应答的CD8+T细胞。
MACSima imaging cyclic staining (MICS) technology reveals combinatorial target pairs for CAR T cell treatment of solid tumors.
许多关键的研究进展利用了在单细胞水平上结合高分辨率与高内涵表征的技术。
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