胶质母细胞瘤的代谢与翻译后脆弱性:二硫死亡、糖基化及对 CAR-T 治疗的启示
Metabolic and Post-Translational Vulnerabilities of Glioblastoma: Disulfidptosis, Glycosylation, and Implications for CAR-T Therapy.
胶质母细胞瘤(GB)仍是治疗抵抗性最强的实体瘤之一,其特征是显著的代谢可塑性、瘤内异质性和高度免疫抑制的微环境。
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Metabolic and Post-Translational Vulnerabilities of Glioblastoma: Disulfidptosis, Glycosylation, and Implications for CAR-T Therapy.
胶质母细胞瘤(GB)仍是治疗抵抗性最强的实体瘤之一,其特征是显著的代谢可塑性、瘤内异质性和高度免疫抑制的微环境。
Challenges and breakthroughs: current landscape and future prospects of CAR-T cell therapy clinical trials for solid tumors.
CAR-T 细胞疗法在血液系统恶性肿瘤的治疗中已显示出显著疗效;然而,其在实体瘤中的应用仍面临挑战。
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