CELL INTELLIGENCE · 肿瘤细胞治疗研究

CAR+ 细胞外囊泡预测接受靶向 CD19 的 CAR-T 细胞治疗的 B 细胞淋巴瘤患者的 ICANS

CAR+ extracellular vesicles predict ICANS in patients with B cell lymphomas treated with CD19-directed CAR T cells.

CD19.CAR-T 细胞来源的细胞外囊泡表达 CAR 并杀伤白血病细胞，参与抗肿瘤治疗

CD19.CAR T-cell-derived extracellular vesicles express CAR and kill leukemic cells, contributing to antineoplastic therapy.

淋巴细胞清除前外周血细胞特征与 CD19 靶向 CAR-T 细胞相关神经毒性相关

Peripheral blood cellular profile at pre-lymphodepletion is associated with CD19-targeted CAR-T cell-associated neurotoxicity.

我们的数据支持 CAR-T 治疗前全身性炎症与 ICANS 相关的观点。

淋巴瘤来源细胞外囊泡抑制 CAR-T 细胞功能

Lymphoma-derived extracellular vesicles inhibit CAR T cell function.