CAR-T 细胞治疗儿童脑肿瘤:附临床试验入组标准比较分析的叙述性综述
CAR T-cell therapy in pediatric brain tumors: a narrative review with comparative analysis of clinical trial eligibility criteria.
符合纳入标准的研究共18项,包括临床前模型、早期临床试验和转化研究。
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CAR T-cell therapy in pediatric brain tumors: a narrative review with comparative analysis of clinical trial eligibility criteria.
符合纳入标准的研究共18项,包括临床前模型、早期临床试验和转化研究。
The safety and efficacy of GD2-targeted CAR-T cells in patients with neuroblastoma: a systematic review and meta-analysis.
靶向 GD2 抗原的 CAR-T 细胞疗法在治疗 NB 方面前景广阔。
Comparative Preclinical Analysis of Anti-B7-H3 CAR-T Cells Targeting Neuroblastoma.
背景:神经母细胞瘤是一种儿童肿瘤,高危患者一旦复发通常致命。
Interplay Between the Epigenome, the Microenvironment, and the Immune System in Neuroblastoma.
神经母细胞瘤(NB)是儿童最常见的颅外肿瘤,也是儿童癌症死亡的第三大原因。
Immunotherapeutic advances in pediatric neuroblastoma: Overcoming resistance through biomarker-guided combinations.
它仍是重大的治疗挑战,尤其是在高危病例中,尽管接受强化多模式治疗,长期生存率仍低于 50%。
Therapeutic Innovation in Pediatric Neuroblastoma: Age and Stage-Specific Strategies from Prenatal to Early Childhood-A Review Article.
治疗的进步带来了希望,但在这类复杂的儿童恶性肿瘤中,实现持久缓解和改善生存仍需要深入的研究创新,以解决当前的空白和耐药机制。
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