糖皮质激素受体激活重编程 NK 细胞以驱动 AREG 介导的免疫抑制:AREG 的泛癌作用
Glucocorticoid Receptor Activation Reprograms NK Cells to Drive AREG-Mediated Immunosuppression: A Pan-Cancer Role for AREG.
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Glucocorticoid Receptor Activation Reprograms NK Cells to Drive AREG-Mediated Immunosuppression: A Pan-Cancer Role for AREG.
Targeting ST3GAL1 to downregulate ligands for the glycoimmune checkpoint Siglec-7 and reverse immune escape in hepatocellular carcinoma.
Multi-omics analysis reveals the role of tumor-infiltrating CD4(+)CCR7(+) T cells in EGFR antibody resistance and prognosis of hepatocellular carcinom
我们的研究结果表明,HCC 中中央记忆 CD4+CCR7+ T 细胞浸润升高与免疫抑制性肿瘤微环境相关,这可能导致了 EGFR 靶向抗体疗效受损以及更差的临床结局。
Mechanisms and network pharmacological analysis of Yangyin Fuzheng Jiedu prescription in the treatment of hepatocellular carcinoma.
FZP 被发现是 YFJP 中发挥抗肿瘤和免疫调节作用对抗 HCC 的关键拆方。FZP 通过 HCC 相关靶点、通路和生物学过程缓解 T 细胞耗竭并改善免疫抑制微环境。
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