基于器官囊过滤的胰腺靶向脂质纳米颗粒
Pancreatic-targeted lipid nanoparticles based on organ capsule filtration.
实现胰腺靶向递送是治疗胰腺疾病的一项突破,但精准递送仍具挑战性 1。
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Pancreatic-targeted lipid nanoparticles based on organ capsule filtration.
实现胰腺靶向递送是治疗胰腺疾病的一项突破,但精准递送仍具挑战性 1。
SLC25A51 mRNA-LNP Armors T Cells with Mitochondrial Fitness in Cancer Treatment.
由于代谢恶劣的肿瘤微环境损害线粒体功能,胰腺导管腺癌对过继性 T 细胞疗法仍大多难治。
Novel mRNA-Engineered Fully Human CAR-T Cells Targeting AXL in Solid Tumors.
结果:流式细胞术证实 CAR 呈短暂但高表达(24 h 时 >90%),且 T 细胞活力保持(>90%)。
mRNA vaccines in cancer immunotherapy: current progress and perspectives in solid tumors and hematologic malignancies.
COVID-19大流行期间mRNA疫苗的空前成功加速了基于核酸的治疗方法的发展,尤其是在肿瘤学领域。
The transformative potential of mRNA vaccines for glioblastoma and human cancer: technological advances and translation to clinical trials.
mRNA 疫苗最初是为控制癌症而设计,如今已作为控制传染病的有效工具跻身医学前沿,其在抗击 COVID-19 大流行中的关键作用尤为突出。
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