肿瘤细胞治疗研究
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Dual CAR-NK cells targeting PD-L1 and ErbB2 (HER2) exhibit cooperative CAR signaling and counteract solid tumor heterogeneity.
同时靶向 PD-L1 与 ErbB2 可通过对抗原异质性提供抵抗力并经协同激活放大抗肿瘤信号，增强 CAR-NK 细胞对难治性实体瘤的疗效。
Overcoming Therapy Resistance in Ovarian Cancer: From Molecular Mechanisms to Emerging Therapeutic Strategies.
背景/目的：上皮性卵巢癌（EOC）仍是一种预后较差的妇科恶性肿瘤，晚期疾病的5年生存率约为29%。
Chimeric antigen receptor-natural killer cell therapy in first-relapse epithelial ovarian cancer: an early health-economic evaluation in the Netherlan
CAR-NK 细胞疗法对铂敏感 EOC 可能具有成本效益。
Repurposing anti-mesothelin CAR-NK immunotherapy against colorectal cancer.
我们的结果提供了临床前证据，表明表达高水平间皮素的结直肠癌亚群可被基于 MSLN-CAR 的免疫治疗有效靶向。
Current Developments of CAR-T and CAR-NK Cell Therapies for Ovarian Cancer.
卵巢癌（OC）仍是最致命的妇科恶性肿瘤，其特征为诊断晚、肿瘤异质性和化疗耐药，导致生存率低。
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