CELL INTELLIGENCE · 肿瘤细胞治疗研究

mRNA-LNP 制备的 CAR-NK 细胞在体外和体内杀伤肿瘤靶细胞

CAR-NK Cells Generated with mRNA-LNPs Kill Tumor Target Cells In Vitro and In Vivo.

一举两得：用现货型双 CAR NK-92 细胞靶向 B 细胞恶性肿瘤中的 BCMA 与 CD19

Two for one: targeting BCMA and CD19 in B-cell malignancies with off-the-shelf dual-CAR NK-92 cells.

在此，我们利用经临床验证的 NK-92 细胞系作为治疗性细胞来源，建立了一个易于获取且灵活的平台，用于生成高度功能化的双靶向 CAR-NK 细胞。

招募体外转录 mRNA 用于肿瘤免疫治疗：当前格局的当代评估

Recruiting In Vitro Transcribed mRNA against Cancer Immunotherapy: A Contemporary Appraisal of the Current Landscape.