实体瘤细胞治疗进展:欧洲视角与未来方向
Advances in cell therapy for solid tumours: European perspective and future directions.
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Advances in cell therapy for solid tumours: European perspective and future directions.
Tumour-infiltrating lymphocyte therapy comes of age in the era of genetic engineering.
TMED inhibition suppresses cell surface PD-1 expression and overcomes T cell dysfunction.
我们的结果揭示了 PD-1 调控的一种新机制,并鉴定出一个在药理学上可干预的靶点,抑制该靶点可抑制 PD-1 丰度与 T 细胞功能障碍。
Uncoupling CD4+ TIL-Mediated Tumor Killing from JAK-Signaling in Melanoma.
我们的数据表明,利用肿瘤特异性细胞毒性 CD4+ TIL 可能有助于克服 MHCIIconst+ 黑色素瘤中由 IFN 信号缺失介导的 ICB 耐药。参见 Betof Warner 和 Luke 的相关评论,第 3829 页。
Highly efficient gene knockout in tumor-infiltrating lymphocytes by adenine base editing.
ProS1-MerTK signaling in CD4 T cells: implications for TIL expansion and functionality.
Tumor-Infiltrating Lymphocytes and Adoptive Cell Therapy: State of the Art in Colorectal, Breast and Lung Cancer.
Novel strategies to improve efficacy of treatment with tumor-infiltrating lymphocytes (TILs) for patients with solid cancers.
Highly efficient PD-1-targeted CRISPR-Cas9 for tumor-infiltrating lymphocyte-based adoptive T cell therapy.
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