肿瘤细胞治疗研究
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Tertiary lymphoid structures correlate with the therapeutic efficacy and prognosis of resectable esophageal squamous cell carcinoma undergoing neoadju
NRCI治疗相比NCI治疗显著改善了可切除ESCC的预后。TLS的分布和丰度与ESCC的OS明显相关，并在NRCI治疗中作为OS的独立预后指标。NRCI治疗通过促进M-TLS的增殖和活化，延长了OS并增强了抗肿瘤免疫反应。
Lympho-myeloid aggregate-infiltrating CD20(+) B cells display a double-negative phenotype and correlate with poor prognosis in esophageal squamous cel
根据形态学特征，肿瘤浸润 B 细胞（TIL-B）可分为淋巴-髓系聚集体（LMA）和三级淋巴结构（TLS）。
Comparative study of the tumor-infiltrating lymphocytes before and after neoadjuvant chemoimmunotherapy in esophageal squamous cell carcinoma.
对于接受新辅助化免治疗的ESCC患者，达到pCR的患者具有更活跃的免疫反应，且不依赖于治疗前PD-L1表达水平，治疗前CD4 + TILs比例可能是其生存的预测因素之一。
Impacts of tumor microenvironment during neoadjuvant chemotherapy in patients with esophageal squamous cell carcinoma.
我们研究了接受新辅助化疗（NAC）后手术的ESCC患者（n = 264）中TME状态及其变化对生存的影响。
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