CELL INTELLIGENCE · 肿瘤细胞治疗研究

CAR-T 治疗的疗效、安全性和成本效果

Efficacy, safety and cost-effectiveness of CAR-T therapy.

利用旁分泌 SIRPγ 衍生的 CD47 阻断剂增强抗 EGFRvIII CAR-T 细胞治疗对胶质母细胞瘤的疗效

Enhancing anti-EGFRvIII CAR T cell therapy against glioblastoma with a paracrine SIRPγ-derived CD47 blocker.

治疗强度会影响免疫重建，即使在未接受造血干细胞移植治疗的儿童癌症患者中也是如此

Treatment intensity affects immune reconstitution even after childhood cancer not treated with hematopoietic stem cell transplantation.

我们的数据表明，在大多数当前儿科肿瘤治疗后，所研究的免疫学参数可快速恢复。针对高危急性淋巴细胞白血病、急性髓系白血病、髓母细胞瘤和成熟 B 细胞淋巴瘤的治疗，与相当比例病例的免疫恢复时间延长相关。高治疗强度与免疫恢复延长相关。

将 CAR-T 细胞引入脑内的特殊挑战：儿童中枢神经系统肿瘤治疗的临床应用展望

The peculiar challenge of bringing CAR-T cells into the brain: Perspectives in the clinical application to the treatment of pediatric central nervous

CAR-T 细胞疗法在儿童脑肿瘤中的潜力

CAR T Cell Therapy's Potential for Pediatric Brain Tumors.