基于 mRNA 的实体瘤癌症疫苗的临床转化
Clinical translation of mRNA-based cancer vaccines for solid tumors.
肿瘤细胞治疗研究
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把在研试验和前沿论文合在一起看,按时间倒序排列。本页条数 = 前沿论文 + 临床试验两块之和(导航里的「临床试验」板块只收在招的那部分,不另计入)。
Clinical translation of mRNA-based cancer vaccines for solid tumors.
mRNA vaccines in cancer immunotherapy: current progress and perspectives in solid tumors and hematologic malignancies.
Does human cytomegalovirus provide a novel therapeutic target for patients with glioblastoma?
Preclinical efficacy of multi-targeting mRNA-based CAR T cell therapy in resection models of glioblastoma.
The transformative potential of mRNA vaccines for glioblastoma and human cancer: technological advances and translation to clinical trials.
mRNA-based precision targeting of neoantigens and tumor-associated antigens in malignant brain tumors.
我们已建立了一种个性化且可定制的 mRNA 治疗方法,能够有效靶向多种肿瘤抗原,并在临床前脑肿瘤模型中展示了强效的抗肿瘤反应。该平台 mRNA 技术独特地解决了肿瘤异质性和低抗原负荷的难题,这两个关键缺陷是靶向经典免疫治疗耐药的 CNS 恶性肿瘤以及可能的其他冷肿瘤类型时所面临的。
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