靶向 ICAM1 的共刺激通过与 TCR 信号协同将 HER2 CAR T 细胞毒性扩展至 HER2 低表达和 HER2 阴性肿瘤
ICAM1-targeted costimulation extends HER2 CAR T cytotoxicity to HER2-low and HER2-negative tumors through synergy with TCR signaling.
自体T细胞经工程化表达HER2嵌合抗原受体(CAR)后,临床疗效有限。
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ICAM1-targeted costimulation extends HER2 CAR T cytotoxicity to HER2-low and HER2-negative tumors through synergy with TCR signaling.
自体T细胞经工程化表达HER2嵌合抗原受体(CAR)后,临床疗效有限。
Chimeric Antigen Receptor-T Cell and Oncolytic Viral Therapies for Gastric Cancer and Peritoneal Carcinomatosis of Gastric Origin: Path to Improving C
精准免疫肿瘤学依靠识别并靶向肿瘤特异性抗原,以增强抗肿瘤免疫并改善实体瘤的治疗结局。
Brave new world-new and emerging treatments for gastric cancer.
对于约 20% 存在人表皮生长因子受体 2(HER2)过表达的胃癌(GC),近期已确立了以曲妥珠单抗形式加用 HER2 阳性靶向治疗的作用。
Recent advances in immune-based approaches for the treatment of esophagogastric cancer.
免疫治疗,特别是免疫检查点抑制剂(ICI)类药物类别的引入,近年来改变了许多癌症的治疗范式。抗PD-1疗法现已成为局部和晚期疾病患者的新标准治疗。
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