聚合物氟嘧啶 CF10 通过 TS/Top1 双重靶向激活适应性抗肿瘤免疫反应
Activation of an adaptive antitumor immune response by the polymeric fluoropyrimidine CF10 involves TS/Top1 dual targeting.
肿瘤细胞治疗研究
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Activation of an adaptive antitumor immune response by the polymeric fluoropyrimidine CF10 involves TS/Top1 dual targeting.
Co-blocking TIGIT and PVRIG Using a Novel Bispecific Antibody Enhances Antitumor Immunity.
Enhanced efficacy of dual chimeric antigen receptor-T cells targeting programmed death-ligand 1 and cancer-associated fibroblasts in colorectal cancer
本研究成功开发了靶向 PD-L1 和 CAF 的双靶点 CAR-T 细胞,并证明其在 CRC 治疗中具有优越的抗肿瘤活性和免疫调节作用。
Design and development of dual targeting CAR protein for the development of CAR T-cell therapy against KRAS mutated pancreatic ductal adenocarcinoma u
Preclinical imaging evaluation of a bispecific antibody targeting hPD1/CTLA4 using humanized mice.
结果表明,将 124 I-AK104 转化为筛选免疫治疗获益患者的方法具有潜力,并且该方法的有效性及可行性已通过人源化小鼠的免疫-PET 成像得到验证。
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