肿瘤细胞治疗研究
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Next-generation antibody-based therapeutics in cancer: antibody-drug conjugates bispecific antibodies across hematologic malignancies and solid tumors
肿瘤学的治疗范式正在经历由抗体药物偶联物（ADC）和双特异性抗体（bsAb）驱动的深刻变革。
Agrimol B induces apoptosis and ferroptosis in acute monocytic leukemia by targeting EGFR/ERK1/2 signaling and activating SIRT1.
这些发现表明，Agrimol B通过多种机制发挥强效抗白血病活性，突显其作为AMoL治疗候选药物的潜力。
Targeting of acute myeloid leukemia by five-gene engineered T cells expressing transgenic T-cell receptor specific to WT1, chimeric antigenic receptor
所提出的策略利用单个piggyBac转座子载体，通过插入TCR、CAR、BiTE构建体以及tEGFR基因自杀系统，实现了T细胞特异性针对急性髓系白血病的复杂重定向。
c-Met is a chimeric antigen receptor T-cell target for treating recurrent nasopharyngeal carcinoma.
我们发现c-Met在rNPC组织中高表达，并证实其作为rNPC的CAR-T靶点的潜力。我们的研究为rNPC的临床治疗提供了新思路。
Impact of Chronic Kidney Disease and Acute Kidney Injury on Safety and Outcomes of CAR T-Cell Therapy in Lymphoma Patients.
CAR-T后发生CKD或AKI对术后OS和PFS无影响。
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