CELL INTELLIGENCE · 肿瘤细胞治疗研究

用于精准肿瘤治疗的嵌合纳米抗体-颗粒酶 B 功能化铁蛋白纳米颗粒的研制

Development of chimeric Nanobody-Granzyme B functionalized ferritin nanoparticles for precise tumor therapy.

免疫功能低下患者 EB 病毒感染的治疗

Treatment of Epstein-Barr Virus infection in immunocompromised patients.

Claudin18.2-CAR-T 细胞治疗转移性胃癌靶病灶完全缓解

Metastatic gastric cancer target lesion complete response with Claudin18.2-CAR T cells.

DKK1 抑制联合 NKG2D CAR-T 细胞治疗胃癌

Combination therapy of DKK1 inhibition and NKG2D chimeric antigen receptor T cells for the treatment of gastric cancer.

αβ和γδ T 细胞对 Epstein-Barr 病毒的反应：移植患者免疫能力、免疫失败及治疗增强的见解

αβ and γδ T-cell responses to Epstein-Barr Virus: insights in immunocompetence, immune failure and therapeutic augmentation in transplant patients.

用于 EBV 相关恶性肿瘤治疗的靶向裂解性 EBV 抗原 CAR-T 细胞的 GMP 开发与临床前验证

GMP development and preclinical validation of CAR-T cells targeting a lytic EBV antigen for therapy of EBV-associated malignancies.

这些结果支持将用 ZT002 生成的 gp350CAR-T 细胞作为创新新药，用于治疗实体和血液 EBV 相关恶性肿瘤患者。

PD-L1 表达与 CD8 阳性淋巴细胞在人类肿瘤中的研究：一项基于 11, 838 例肿瘤样本的组织芯片研究

PD-L1 expression and CD8 positive lymphocytes in human neoplasms: A tissue microarray study on 11,838 tumor samples.

PD-L1 在肿瘤细胞和炎症细胞中的表达见于多种人类肿瘤类型。PD-L1 阳性癌症中肿瘤浸润 CD8 阳性淋巴细胞的比例高于 PD-L1 阴性癌症，提示抗肿瘤免疫反应可能触发肿瘤 PD-L1 表达。

CD19 CAR-T 细胞成功治疗同时性滤泡性淋巴瘤与胃腺癌 1 例并文献复习

Successful treatment of a case with synchronous follicular lymphoma and gastric adenocarcinoma with CD19 CAR T cells and literature review.

胃癌免疫治疗的进展

Immunotherapeutic advances in gastric cancer.