CELL INTELLIGENCE · 肿瘤细胞治疗研究

下一代基于抗体的癌症治疗：抗体-药物偶联物和双特异性抗体在血液系统恶性肿瘤和实体瘤中的应用

Next-generation antibody-based therapeutics in cancer: antibody-drug conjugates bispecific antibodies across hematologic malignancies and solid tumors

平行处理 T 细胞与 NK 细胞以增强体内 CAR-T 细胞对血液肿瘤和实体瘤的活性

Parallel processing of T cells and natural killer cells to enhance in vivoCAR T cell activity against blood and solid cancers.

本研究鼓励优化利用白细胞单采产物。通过将废弃的 PBMC 回收为 NK 细胞，可有效增强 CAR-T 细胞疗法，改善肿瘤清除率和生存率。

预测性 14 基因特征与 FLI1 抑制克服三阴性乳腺癌中 TIL（肿瘤浸润淋巴细胞）功能障碍

A predictive 14-gene signature and FLI1 inhibition overcome tumor-infiltrating lymphocyte dysfunction in triple-negative breast cancer.

分析乳腺癌未知原发灶中的癌症干细胞机制和免疫特征

Analysis of cancer stem cell mechanism and immune profiling in breast cancer of unknown primary.

靶向 PIM2 通过促进 CD8 T 细胞的效应功能和持久性增强抗肿瘤免疫

Targeting PIM2 improves antitumor immunity through promoting effector function and persistence of CD8 T cells.

探索肿瘤中的 SLAMF5/CD84：推进肿瘤免疫学前沿

Exploring SLAMF5/CD84 in Cancer: Advancing the Frontiers of Tumor Immunology.

PML 在三阴性乳腺癌肿瘤相关巨噬细胞中的定位作为预后标志物

PML localization in tumor associated macrophages as a prognostic marker in triple negative breast cancer.

肿瘤来源的细胞外囊泡在 NK 细胞免疫逃逸中的作用：分子机制与治疗启示

Cancer-derived extracellular vesicles in natural killer cell immune evasion: Molecular mechanisms and therapeutic insights.

进入场景：T(H)9 细胞向肺部优越的迁移能力解释了其卓越的抗癌疗效

Go to the scene: T(H)9 cells superior migration ability to the lungs explains their exceptional anticancer efficacy.

血液系统恶性肿瘤患者 CAR-T 细胞治疗后的第二原发恶性肿瘤

Second primary malignancies following CAR T-cell therapy in patients with hematologic malignancies.