CELL INTELLIGENCE · 肿瘤细胞治疗研究

CAR-T 细胞治疗胰腺癌的进展、挑战与创新策略

Advances, challenges, and innovative strategies of CAR-T cell therapy in pancreatic cancer.

携带 IL-12 的溶瘤 HSV-2 增强 CAR-T 细胞在异种移植模型中对胰腺癌的疗效

IL-12-armed oncolytic HSV-2 enhances CAR T cell efficacy against pancreatic cancer in xenografted models.

这种协同策略以降低的 CAR-T 剂量实现了持久而强效的肿瘤清除，为胰腺癌及其他具有挑战性的实体恶性肿瘤提供了一种变革性策略。

MSLN 靶向肿瘤治疗的新视角：从分子机制到临床转化

Novel perspectives on MSLN-targeted cancer therapy: from molecular mechanisms to clinical translation.

溶瘤疱疹病毒增强 CAR 靶抗原表达对间皮素 CAR-T 细胞治疗胰腺癌的增效作用

Enhancing mesothelin CAR T cell therapy for pancreatic cancer with an oncolytic herpes virus boosting CAR target antigen expression.

溶瘤腺病毒 AdV5/3-D24-ICOSL-CD40L 联合抗 PD-1 的新型组合疗法通过促进肿瘤内 T 细胞浸润和调节肿瘤微环境在间皮瘤小鼠模型中展现出增强的抗癌疗效

Novel combinatorial therapy of oncolytic adenovirus AdV5/3-D24-ICOSL-CD40L with anti PD-1 exhibits enhanced anti-cancer efficacy through promotion of

恶性胸膜间皮瘤不断演变中的治疗格局

The Evolving Therapeutic Landscape for Malignant Pleural Mesothelioma.