异基因 iPSC 来源 γδT 细胞对患者来源组织显示抗肿瘤疗效
Allogeneic iPSC-derived γδT cells demonstrate antitumor efficacy against patient-derived tissues.
肿瘤细胞治疗研究
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把在研试验和前沿论文合在一起看,按时间倒序排列。本页条数 = 前沿论文 + 临床试验两块之和(导航里的「临床试验」板块只收在招的那部分,不另计入)。
Allogeneic iPSC-derived γδT cells demonstrate antitumor efficacy against patient-derived tissues.
Elotuzumab enhances the anti-tumor activity of Vγ9Vδ2 T cells against primary effusion lymphoma.
Genetic disruption of Pdcd-1 upstream enhancer boosts T cell function and antitumor responses.
A probiotic bacterium modulates antitumour γδ T-cell responses in lung cancer.
Functional and structural analysis of KK-LC-1-specific T cell receptors from patients with lung Cancer for immunotherapy.
A Super-Aged Patient with Primary Cutaneous Gamma-Delta T-Cell Lymphoma Treated with Palliative Radiotherapy: A Short-Term Follow-Up Case.
尽管 PCGDTL 已知对化疗和放疗反应均较差,但本例表明,局部放疗作为一种低毒性选择,可能在部分老年患者中实现暂时性效果。本报告为 PCGDTL 非化疗为基础的管理策略的有限文献增添了内容,并强调了在体弱或超高龄患者中个体化治疗策略的重要性。
Elotuzumab-mediated ADCC with Th1-like Vγ9Vδ2 T cells to disrupt myeloma-osteoclast interaction.
Analysis of the Effector Functions of Vδ2 γδ T Cells and NK Cells against Cholangiocarcinoma Cells.
Ex vivo expansion and activation of Vγ9Vδ2 T cells by CELMoDs in combination with zoledronic acid.
Roles of tumor necrosis factor-like ligand 1A in γδT-cell activation and psoriasis pathogenesis.
这些发现提示了 TL1A 对γδT 细胞的一种新型调控机制,并表明其作为潜在治疗靶点参与银屑病发病机制。
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