联合免疫治疗驱动小鼠肾肿瘤微环境中肿瘤抗原特异性 CD8⁺ T 细胞耗竭
Combinatorial immunotherapy drives exhaustion in tumor antigen-specific CD8+ T cells within the mouse renal tumor microenvironment.
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FRONTIER PAPERS
Combinatorial immunotherapy drives exhaustion in tumor antigen-specific CD8+ T cells within the mouse renal tumor microenvironment.
VHL and DNA damage repair pathway alterations as potential clinical biomarkers for first-line TKIs in metastatic clear cell renal cell carcinomas.
我们发现,携带 DDR 和 VHL 改变的 mccRCC 患者比野生型患者更可能从一线 VEGF-TKI 系统性治疗中获益。
Functionally Characterizing the Renal Cell Carcinoma Tumor-Immune Microenvironment via Patient-Derived Ex Vivo Models.
Therapeutic Management of Metastatic Clear Cell Renal Cell Carcinoma: A Revolution in Every Decade.
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