CELL INTELLIGENCE · 肿瘤细胞治疗研究

基于包被溶瘤病毒的“双重打击”策略在胃肠道肿瘤中触发 CD19 CAR-T 治疗

Coated oncolytic viruses based "double strike" strategy triggering CD19 CAR-T therapy in gastrointestinal tumors.

靶向 EpCAM 的 CAR-T 细胞疗法 IMC001 的临床前开发及其在晚期胃癌患者中的 1 期试验

Preclinical development and a phase 1 trial of IMC001, an EpCAM-targeted CAR-T cell therapy, in patients with advanced gastric cancer.

CAR-T 细胞疗法在实体瘤中的挑战与展望：来自胃癌的启示

Challenges and perspectives of CAR-T cell therapy in solid tumours: insights from gastric cancer.

胃癌中靶向上皮细胞黏附分子的 CAR-T 细胞治疗：肿瘤耐药机制

Chimeric Antigen Receptor T Cell Therapy Targeting Epithelial Cell Adhesion Molecule in Gastric Cancer: Mechanisms of Tumor Resistance.

快速分离胃腺癌肿瘤干细胞作为自体树突状细胞免疫治疗的靶点

Rapid Isolation of Gastric Adenocarcinoma Cancer Stem Cells as a Target for Autologous Dendritic Cell-Based Immunotherapy.

我们提出，球体形成实验和致瘤性实验是两种方法，可快速分离具有特定干性特征的癌细胞，以便利用自体树突状细胞疗法靶向 CSCs，尤其是在晚期疾病患者中。