单细胞视角下受体介导精准癌症联合治疗的全景
The landscape of receptor-mediated precision cancer combination therapy via a single-cell perspective.
本研究提供了对选择性且精准靶向癌症所需联合靶点的身份和数量的计算估计。
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The landscape of receptor-mediated precision cancer combination therapy via a single-cell perspective.
本研究提供了对选择性且精准靶向癌症所需联合靶点的身份和数量的计算估计。
Dual targeting of solid tumors using cytokine-induced killer cells modified with a CAR anti-tenascin C and a secretable EGFRxCD3 bispecific antibody.
我们得出结论,CAR-TNC5联合EGFRxCD3能够赋予CIK细胞在体内不同且可能协同的功能。
The peptide-based bispecific CAR T cells target EGFR and tumor stroma for effective cancer therapy.
我们的研究结果表明,基于肽的双特异性CAR T细胞因其对肿瘤及肿瘤微环境的出色靶向能力,在实体瘤治疗中展现出巨大潜力。
Dual Targeting of Glioblastoma Cells with Bispecific Killer Cell Engagers Directed to EGFR and ErbB2 (HER2) Facilitates Effective Elimination by NKG2D
我们的结果表明,将携带活化NKAR受体的NK细胞与双特异性NKAB抗体联合使用,可实现灵活靶向,从而增强肿瘤抗原特异性细胞毒性并防止免疫逃逸。
Tumor cell lysis and synergistically enhanced antibody-dependent cell-mediated cytotoxicity by NKG2D engagement with a bispecific immunoligand targeti
通过将IgG1抗体与靶向另一种肿瘤相关抗原并接合NKG2D作为第二NK细胞触发分子的抗体构建体相结合,双-双靶向策略可能具有前景。
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