双重靶向肿瘤代谢组和应激抗原影响工程化 T 细胞的转录组异质性和疗效
Dual targeting of cancer metabolome and stress antigens affects transcriptomic heterogeneity and efficacy of engineered T cells.
少数癌症可以通过工程化 T 细胞策略有效靶向。
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Dual targeting of cancer metabolome and stress antigens affects transcriptomic heterogeneity and efficacy of engineered T cells.
少数癌症可以通过工程化 T 细胞策略有效靶向。
BiTE-Secreting CAR-γδT as a Dual Targeting Strategy for the Treatment of Solid Tumors.
HLA-G 被认为是一种免疫检查点蛋白和肿瘤相关抗原。
Activation of an adaptive antitumor immune response by the polymeric fluoropyrimidine CF10 involves TS/Top1 dual targeting.
在体内,对携带原位 MC38 肝转移的 C57BL/6 小鼠进行 CF10 治疗,可增加 CD4⁺、CD8⁺和γδ T 细胞浸润,减少髓源性抑制细胞(MDSCs),并降低肝脏肿瘤负荷。
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