CELL INTELLIGENCE · 肿瘤细胞治疗研究

通过靶向 TROP2 的 CAR-T 细胞疗法清除 EGFR 突变非小细胞肺癌中的耐药持留细胞

Eradicating Drug-tolerant Persister Cells in EGFR-Mutated Non-Small Cell Lung Cancer by Targeting TROP2 with CAR-T Cellular Therapy.

小细胞肺癌的新兴疗法与转化进展：克服耐药性

Emerging therapies and translational advances in small cell lung cancer: Overcoming resistance.

Anti-Trop2 CAR-NK（NK 细胞）治疗非小细胞肺癌：I/II 期临床试验

Clinical Study of Trop2 CAR-NK in the Treatment of Relapsed/Refractory Non-Small Cell Lung Cancer (NSCLC)

这是一项 I/II 期注册临床试验，评估 NK 细胞治疗非小细胞肺癌的疗效与安全性。当前状态：尚未开始招募。计划入组 50 例。登记号：NCT06454890。

射频消融联合 TROP2-CAR-T 细胞在肺腺癌异种移植小鼠模型中的协同抗肿瘤疗效

Synergistic Antitumor Efficacy of Radiofrequency Ablation Combined With TROP2-CAR-T Cells in a Xenograft Mouse Model of Lung Adenocarcinoma.

RFA 与 TROP2-CAR-T 疗法联合在 LUAD 中显示出增强的抗肿瘤疗效和改善的安全性特征，凸显了一种有前景的联合免疫治疗策略。

过继性细胞治疗在小细胞肺癌中的进展

Advances in adoptive cell therapies in small cell lung cancer.